Case 32 | Clinical Pathology Unknown Conference

1. Presented by Eric A. Gehrie, MD and prepared by Lorraine N. Blagg, MA, MLS(ASCP)SBB

Clinical Vignette

An adult patient with recent history of an aortic dissection was admitted after presenting to the clinic with abdominal pain, nausea and vomiting. The patient subsequently had surgery to repair the dissection, requiring RBC and plasma transfusions. Several days after surgery a type and screen was sent to the blood bank. The results of the type and screen revealed the patient to be group B, Rh Positive with a positive antibody screen.

Antibody Identification Panel:

The patient received one more RBC unit after identification of the antibody and a new type and screen was received three days later with a result of B Positive, and a positive antibody screen with the following additional testing results.

Antibody Identification Panel:

Direct Antiglobulin (DAT) Battery:

Elution Testing:

Question:
What is the interpretation of the immunohematology serologic workup?

Anti-C identified prior to a delayed serologic transfusion reaction caused by anti-S

Anti-S identified prior to a delayed serologic transfusion reaction caused by anti-C

Anti-Jk^a identified prior to a delayed serologic transfusion reaction caused by anti-C

Anti-C identified prior to a delayed serologic transfusion reaction caused by anti-Jk^a

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