Case 94

1. Presented by Gabrielle Bailey, MD and reviewed by Lorraine N. Blagg, MA, MLS(ASCP)SBB

A pediatric patient with a history of leukemia undergoing chemotherapy is admitted to the hospital for febrile neutropenia detected during an outpatient visit. They were found to have B.cereus bacteremia and an angioinvasive Rhizopus skin infection. They were treated with Levofloxacin and cefazolin for their B.cereus bacteremia, as well as Amphotericin B for the Rhizopus infection. They remained febrile during their admission and their absolute neutrophil count remained critically low (0.00 to 0.09 K/cu mm). Additionally, they had diarrhea with CT evidence of colitis. Due to their declining clinical course, the team is now requesting granulocyte transfusions.

Which one of the following statements is true about granulocyte transfusions?