Transfusion Medicine Case 10 May 3, 2023 pathadmin 2,120 Comments 1. Presented by Parvez Lokhandwala MD, PhD and prepared by Jackie Birkness, MDClinical VignetteThe patient is a young adult multigravida presenting to labor and delivery with contractions. You receive a call from an obstetrics and gynecology resident who wants to know if the patient should receive RhoGam. The patient received RhoGam during previous pregnancies, as well as several weeks earlier during this pregnancy because she was typed as D- at an outside hospital. However, laboratory testing at your hospital shows a serologic weak D phenotype. RHD genotyping performed at a reference lab shows weak D variant 2.Question:How do you respond to the obstetrics and gynecology resident's question?Since the patient was typed as D- at an outside hospital, she should receive RhoGam if the baby is D+. Patients with weak D never form anti-D, so RhoGam is not necessary. There are no reports of patient with weak D variant 2 forming anti-D. RhoGam is therefore not indicated for this patient. Loading...
