Case 81

1. Prepared by Katya Dombrowski, MD and reviewed by Lorraine N. Blagg, MA, MLS(ASCP)SBB

Clinical vignette
An adult presents to the oncology clinic, where they are being treated for an adenocarcinoma. Labs show a hemoglobin of 4.9 g/dL and thepatient is urgently transfused with one unit of packed red blood cells. At the end of the transfusion, they develops a fever, chills, and rigors. A transfusion reaction work-up is initiated. Of note, the patient has previous history of red blood cell transfusion, most recently three weeks ago.
Plasma: grossly hemolyzed
Transfusion Line: slightly hemolyzed








Question: How can the Direct Antiglobulin Test (DAT) be negative if the antibody screen is positive?

 

45 thoughts on “Case 81”

  1. I’ve found a treasure trove of knowledge in your blog. Your dedication to providing trustworthy information is something to admire. Each visit leaves me more enlightened, and I appreciate your consistent reliability.

  2. Your dedication to sharing knowledge is unmistakable, and your writing style is captivating. Your articles are a pleasure to read, and I consistently come away feeling enriched. Thank you for being a dependable source of inspiration and information.

  3. Your blog has rapidly become my trusted source of inspiration and knowledge. I genuinely appreciate the effort you invest in crafting each article. Your dedication to delivering high-quality content is apparent, and I eagerly await every new post.

  4. I must applaud your talent for simplifying complex topics. Your ability to convey intricate ideas in such a relatable manner is admirable. You’ve made learning enjoyable and accessible for many, and I deeply appreciate that.

  5. In a world where trustworthy information is more crucial than ever, your dedication to research and the provision of reliable content is truly commendable. Your commitment to accuracy and transparency shines through in every post. Thank you for being a beacon of reliability in the online realm.

  6. I must applaud your talent for simplifying complex topics. Your ability to convey intricate ideas in such a relatable manner is admirable. You’ve made learning enjoyable and accessible for many, and I deeply appreciate that.

  7. This article is a true game-changer! Your practical tips and well-thought-out suggestions hold incredible value. I’m eagerly anticipating implementing them. Thank you not only for sharing your expertise but also for making it accessible and easy to apply.

  8. Your enthusiasm for the subject matter radiates through every word of this article; it’s contagious! Your commitment to delivering valuable insights is greatly valued, and I eagerly anticipate more of your captivating content. Keep up the exceptional work!

  9. Your blog is a true gem in the vast expanse of the online world. Your consistent delivery of high-quality content is truly commendable. Thank you for consistently going above and beyond in providing valuable insights. Keep up the fantastic work!

  10. Your writing style effortlessly draws me in, and I find it difficult to stop reading until I reach the end of your articles. Your ability to make complex subjects engaging is a true gift. Thank you for sharing your expertise!

  11. I must commend your talent for simplifying complex topics. Your ability to convey intricate ideas in such a relatable way is admirable. You’ve made learning enjoyable and accessible for many, and I appreciate that.

  12. Wonderful blog! I found it while browsing on Yahoo News.
    Do you have any suggestions on how to get listed in Yahoo News?

    I’ve been trying for a while but I never seem to get there!
    Thanks

  13. What’s up friends, how is everything, and what you wish
    for to say concerning this paragraph, in my view its actually awesome for me.

  14. Hello there! I know this is kind of off topic but I was wondering which blog platform
    are you using for this website? I’m getting fed up of WordPress because I’ve had issues
    with hackers and I’m looking at alternatives for another
    platform. I would be fantastic if you could point me in the direction of a good platform.

  15. It’s a pity you don’t have a donate button! I’d without a doubt donate
    to this fantastic blog! I guess for now i’ll settle for bookmarking and
    adding your RSS feed to my Google account. I look forward to new updates
    and will talk about this website with my Facebook group. Chat soon!

  16. Thanks for one’s marvelous posting! I really enjoyed reading it, you may be a great author.
    I will be sure to bookmark your blog and will often come back
    at some point. I want to encourage you to ultimately continue your
    great job, have a nice day!

Leave a Reply

Your email address will not be published. Required fields are marked *